Title
Topic
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Patent combines drugs with immunotherapy for cancer treatment
“Bouvé/chemical engineering University Distinguished Professor Mansoor Amiji was awarded a patent for ‘Combination Taxoid Nanoemulsion With Immunotherapy in Cancer.'”
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System for closed-loop GNSS
“Electrical and computer engineering associate professor Pau Closas was awarded a patent for ‘System for Closed-Loop GNSS Simulation.'”
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‘Integrating AI into the Front End of New Product Development’
“This study explores the integration of artificial intelligence (AI) into the fuzzy front end (FFE) of new product development (NPD). Using the AI-augmented LUCID platform, we demonstrate how large-scale customer data can be synthesized to enhance decision-making, accelerate concept development, and improve product evaluation efficiency. While traditional NPD methods are time-intensive and rely heavily on subjective expertise, AI streamlines the process by generating and evaluating thousands of design options in real time. Our findings show that AI augments human expertise by identifying critical insights within vast datasets, uncovering previously overlooked opportunities.” Find the paper and authors list in Research-Technology Management.
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‘Root of Unity Quantum Cluster Algebras and Discriminants’
“We describe a connection between the subjects of cluster algebras, polynomial identity algebras, and discriminants. For this, we define the notion of root of unity quantum cluster algebras and prove that they are polynomial identity algebras. Inside each such algebra we construct a (large) canonical central subalgebra, which can be viewed as a far reaching generalization of the central subalgebras of big quantum groups constructed by De Concini, Kac, and Procesi and used in representation theory.” Find the paper and full list of authors in Journal of the London Mathematical Society.
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‘Getting out of South Carolina’s Juvenile Justice System’
Incarcerated juveniles in South Carolina often “receive fewer hours of education than they were getting prior to incarceration, if any. Getting out of South Carolina’s Juvenile Justice System highlights the importance of prevention and community programming, as well as preparation for the return to mainstream society. Through stories from juveniles, parents, judges, prosecutors and defense attorneys, author Kimberly Nolan addresses the issues within the juvenile justice system in South Carolina and offers ideas on how to support young offenders as they navigate both the transition to adulthood and community living.”
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Abowd receives ACM SIGCHI Special Recognition Award
“Gregory D. Abowd, dean of the College of Engineering and professor of electrical and computer engineering, received the Association of Computing Machinery Special Interest Group on Computer-Human Interaction (ACM SIGCHI) Special Recognition Award ‘for his extraordinary ability to inspire and mentor individuals from diverse backgrounds and his commitment to fostering collaboration, creativity, and impact.’ … Awardees’ achievements will be celebrated at the ACM CHI 2025 conference in Yokohama, Japan in April 2025.”
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‘Network Coding for Engineers’
According to the publisher’s webpage, “‘Network Coding for Engineers’ introduces the fundamentals of this exciting subject from an engineering perspective. Beginning with the basics, including step-by-step details for implementing network coding and current applications, it also highlights potential uses of network coding in the communications technologies of the future. The result is an innovative and accessible introduction to a subject quickly becoming indispensable.” Find the full list of authors at Wiley.
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Stevenson selected to receive Young Investigator Award
Assistant professor of physics Paul Stevenson has been selected to receive an Air Force Office of Scientific Research Young Investigator Award “for a new project using quantum sensors to explore electron transport in biomolecules.”
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‘Responses of Littorina spp. Intertidal Snails to Thermal Extremes Indicate Countergradient Variation in Fitness’
“Global change models predict not only a steady increase in temperatures but also an increase in the occurrence of hot and cold extremes. Organisms’ responses to thermal extremes will depend on species-specific traits and the degree of within-species variation (among populations). … The evolution of population-specific responses, however, can be limited by gene flow that homogenises populations. Here, we investigate this relationship with a study of the survival of Littorina littorea, L. obtusata, and L. saxatilis—marine snails with varying dispersal potential—collected on either side of a known biogeographic break.” Find the paper and list of authors in Ecology and Evolution.
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‘A Phosphorylation Signal Activates Genome-Wide Transcriptional Control by BfmR’
“The nosocomial pathogen Acinetobacter baumannii is a major threat to human health. The sensor kinase-response regulator system, BfmS-BfmR, is essential to multidrug resistance and virulence in the bacterium and represents a potential antimicrobial target. Important questions remain about how the system controls resistance and pathogenesis. Although BfmR knockout alters expression of >1000 genes, its direct regulon is undefined. Moreover, how phosphorylation controls the regulator is unclear. Here, we address these problems by combining mutagenesis, ChIP-seq, and in vitro phosphorylation to study the functions of phospho-BfmR.” Find the paper and full list of authors in Nucleic Acids Research.
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‘A Prospective Real-Time Transfer Learning Approach To Estimate Influenza Hospitalizations With Limited Data’
“Accurate, real-time forecasts of influenza hospitalizations would facilitate prospective resource allocation and public health preparedness. State-of-the-art machine learning methods are a promising approach to produce such forecasts, but they require extensive historical data to be properly trained. Unfortunately, data on influenza hospitalizations, for the 50 states in the United States, are only available since the beginning of 2020. In addition, the data are far from perfect as they were under-reported for several months before health systems began consistently submitting their data. To address these issues, we propose a transfer learning approach.” Find the paper and list of authors in Epidemics.
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‘3D Spatial Distribution of Sost mRNA and Sclerostin Protein Expression in Response to In Vivo Tibia Loading in Female Mice’
“Bones adapt to external mechanical loads through a process known as mechanoadaptation. Osteocytes are the bone cells that sense the mechanical environment and initiate a biological response. Investigating the changes in osteocyte molecular expression following mechanical loading has been instrumental in characterizing the regulatory pathways involved in bone adaptation. … In this study, we used WISH-BONE (Whole-mount In Situ Histology of Bone) to investigate the spatial distribution of Sost-mRNA transcripts and its encoded protein, sclerostin, in 3D mouse tibia midshaft following in vivo tibia loading.” Find the paper and full list of authors in Bone.
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‘Human Mobility Is Well Described by Closed-Form Gravity-Like Models Learned Automatically From Data’
“Modeling human mobility is critical to address questions in urban planning, sustainability, public health, and economic development. … At one end of the modeling spectrum we have gravity models, which are easy to interpret but provide modestly accurate predictions of flows. At the other end, we have machine learning models, … which predict mobility more accurately than gravity models but do not provide clear insights on human behavior. Here, we show that simple machine-learned, closed-form models of mobility can predict mobility flows as accurately as complex machine learning models, and extrapolate better.” Find the paper and list of authors in…
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‘Practical Business Analytics Using R and Python’
From the publisher: “This book illustrates how data can be useful in solving business problems. It explores various analytics techniques for using data to discover hidden patterns and relationships, predict future outcomes, optimize efficiency and improve the performance of organizations. You’ll learn how to analyze data by applying concepts of statistics, probability theory, and linear algebra. In this new edition, both R and Python are used to demonstrate these analyses. Practical Business Analytics Using R and Python also features new chapters covering databases, SQL, Neural networks, Text Analytics, and Natural Language Processing.”
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Mosallaei made Optica Fellow
“Electrical and computer engineering professor Hossein Mosallaei was selected as a Fellow of Optica (formerly OSA) for outstanding contributions in active and time-modulated optical nanoantennas and metasurfaces. Optica Fellows are chosen based on several factors, including outstanding contributions to research, business, education, engineering, and service to Optica and its community.”
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‘A Hypothesis: Metabolic Contributions to 16p11.2 Deletion Syndrome’
“16p11.2 deletion syndrome is a severe genetic disorder associated with the deletion of 27 genes from a Copy Number Variant region on human chromosome 16. … We present a hypothesis in which changes in the dosage of 16p11.2 metabolic genes contribute to pathology through direct or indirect alterations in pathways that include amino acids or proteins, DNA, RNA, catabolism, lipid, energy (carbohydrate). This hypothesis suggests that research into the specific roles of each metabolic gene will help identify useful therapeutic targets.” Find the paper and full list of authors in BioEssays.
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‘Data Analytics Adoption, Social Support and Internal Auditor Performance’
“Data analytics are regarded as indispensable in enhancing auditor performance in the era of rapid technology advancements and Big Data. We examine the extent to which social support facilitates internal auditor adoption of data analytics, and whether the use of data analytics is associated with performance. … We document that peer social support developed through coparticipation in company trainings, accelerates the adoption of data analytics in various internal audit tasks including continuous auditing, communication, aligning risks and controls, and aligning data analytics with business control objectives.” Find the paper and full list of authors in Auditing.
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‘Model Supports Asymmetric Regulation Across the Intercellular Junction for Collective Cell Polarization’
“Symmetry breaking, which is ubiquitous in biological cells, functionally enables directed cell movement and organized embryogenesis. Prior to movement, cells break symmetry to form a well-defined cell front and rear in a process called polarization. In developing and regenerating tissues, collective cell movement requires the coordination of the polarity of the migration machineries of neighboring cells. … Here, we investigated how polarity signals are communicated from one cell to its neighbor to ensure coordinated front-to-rear symmetry breaking with the same orientation across the group.” Find the paper and full list of authors in Computational Biology.
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‘Unlocking Hidden Value: How a Job Candidate’s Network Can Drive Your Business Forward’
“As companies strive to stay competitive, having a workforce that brings a wide range of experiences and perspectives is critical. While most hiring processes tend to focus on skills, qualifications, and job experience, there’s an often-overlooked asset that can significantly impact an organization’s success: a candidate’s professional network.”
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Giglio and Friar receive Schulze Publication Award
“Joseph Giglio and John Friar were recently recognized as 2023/24 FamilyBusiness.org Schulze Publication Award recipients for their article, ‘How to Transform an Outdated Board.”’Named after Richard Schulze, founder of Best Buy, this award honors articles that have made a significant impact on FamilyBusiness.org and EIX, based on readership and engagement. Their work stood out for its clarity, insight, and ability to connect research with real-world family business challenges.”
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Eddleston receives Schulze Publication Award
“Kimberly Eddleston, founding editor of FamilyBusiness.org, was recently recognized as the top 2023/24 Schulze Publication Award winner for her outstanding contributions to the platform. Named after Dick Schulze, founder of Best Buy, this prestigious award honors articles that have made a significant impact on EIX and FamilyBusiness.org, based on readership and engagement. Eddleston’s work was selected for its depth of insight, clarity, and ability to translate academic research into actionable knowledge for family business owners, educators, and researchers worldwide.”
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‘Interceptive Abilities in Autism Spectrum Sisorder: Comparing Naturalistic and Virtual Visuomotor Tasks’
“A growing body of research reveals that autistic individuals exhibit motor coordination challenges. Multiple theoretical frameworks propose that the seemingly disparate features of autism may arise from a common underlying process: a diminished ability to make predictions. Sensorimotor skills, such as catching a ball, critically rely on predicting the ball’s trajectory as well as anticipatory coordination of the entire body. Here, we assessed four different naturalistic and virtual interception tasks with 31 neurotypical and 23 autistic children (ages 7–12).” Find the paper and full list of authors in Autism Research.
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‘Spontaneous Anthropocentric Language Use in University Students’ Explanations of Biological Concepts’
“Previous research has shown that students employ intuitive thinking when understanding scientific concepts. Three types of intuitive thinking—essentialist, teleological, and anthropic thinking—are used in biology learning and can lead to misconceptions. … In this study, we examined how frequently undergraduate students across two U.S. universities (N = 807) used construal-consistent language (CCL) to explain in response to open-ended questions related to five core biology concepts (e.g., evolution), how CCL use differed by concept, and how this usage was related to misconceptions agreement.” Find the paper and full list of authors in LSE.
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‘Role of Ryanodine Receptor Cooperativity in Ca 2+ Wave-Mediated Triggered Activity in Cardiomyocytes’
“Ca2+ waves are known to trigger delayed after-depolarizations that can cause malignant cardiac arrhythmias. However, modelling Ca2+ waves using physiologically realistic models has remained a major challenge. Existing models with low Ca 2+ sensitivity of ryanodine receptors(RyRs) necessitate large release currents, leading to an unrealistically large Ca2+ transient amplitude incompatible with the experimental observations. Consequently, current physiologically detailed models of delayed after-depolarizations resort to unrealistic cell architectures. … Here, we address these challenges by incorporatingRyR cooperativity into a physiologically detailed model with a realistic cell architecture.” Find the paper and full list of authors in The Journal of Physiology.
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‘Climate Effects on Belowground Tea Litter Decomposition Depend on Ecosystem and Organic Matter Types in Global Wetlands’
“Patchy global data on belowground litter decomposition dynamics limit our capacity to discern the drivers of carbon preservation and storage across inland and coastal wetlands. We performed a global, multiyear study in over 180 wetlands across 28 countries and 8 macroclimates using standardized litter as measures of “recalcitrant” (rooibos tea) and “labile” (green tea) organic matter (OM) decomposition. … Our study highlights the potential for reduction in belowground OM in coastal and inland wetlands under increased warming.” Find the paper and full list of authors in Environmental Science & Technology.
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Sun receives patent for energy-saving material
“Electrical and computer engineering distinguished professor Nian Sun was awarded a patent for ‘Topological insulator/normal metal bilayers as spin hall materials for spin orbit torque devices, and methods of fabrication of same.'”
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Bai receives patent to strengthen soft materials
“Mechanical and industrial engineering assistant professor Ruobing Bai, in collaboration with Michigan State University, is leading a $705,664 NSF grant for the ‘Mechanics of End-Linked Polymer Networks With Strain-Induced Crystallization Regulated by Topological Defects.’ The research will lead to understanding mechanisms and developing new end-linked polymer networks with desired mechanical properties, which can facilitate emerging applications such as soft robotics, medical devices, and wearable electronics.”
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Patent protecting against side-channel attacks
“Electrical and computer engineering professor and associate dean for faculty affairs Yunsi Fei was awarded a patent for ‘Methods and Systems for Protecting Against Memory-Based Side-Channel Attacks.'”